Search
PROMETEUS
  • Home
  • Mission
  • Project
  • Timeline
  • Participants
  • News
  • Contact
  • Menu Menu
FOLLOW US ON:
  • ⇧ TOP
  • PROGRAMME
  • REGISTRATION

Integrated Structural Biology Approach for Membrane Protein Research
Rome 3rd and 4th March 2022

Sapienza University of Rome, Aula degli Organi Collegiali

Proteins are the functional macromolecules in cells, they are the main drug targets and also used as pharmaceuticals and in biotechnology. Notably, nearly 30% of proteins in eukaryotic cells are known to be membrane proteins.

Although most commercial drugs result from conventional discovery methods, it is the structural information provided by three-dimensional protein structures that unveils the crucial structural arrangement and atomic interactions in drug-protein complexes. This information is critical in the rational design of new drugs with improved selectivity and pharmaceutical properties.

The Workshop will cover advanced methods for the characterization of membrane proteins with a specific focus on drug targets and rational drug design and new structures of membrane proteins.

The main topics will be:
Latest developments in Methods & Facilities
Membrane Proteins functional studies
Structures of membrane proteins relevant for understanding pathologies and drugs design.

Speakers are leading experts in the field from several Academic Institutions (New York Structural Biology Center, Columbia University, Imperial College, IME-Fraunhofer, ITQB-Universidade Nova de Lisboa, Basel Biozentrum, Naples Tigem, Milan University, Pavia University, Calabria University and SME Calixar In France). The Workshop is organized in the context of the the Prometeus MSCA-RISE Project.

Online Attendance Attendance in Person
Watch Day 1 Watch Day 2

PROGRAMME

Registration at Aula degli Organi Collegiali starts on March 3rd, 2022 at 13:30

Day 1 – March 3rd, 2022
Sapienza University of Rome, Aula degli Organi Collegiali

14:00-14:05OPENING

Beatrice Vallone
Sapienza University of Rome

14:00-14:05OPENING

Beatrice Vallone
Sapienza University of Rome

Session 1: Latest developments in Methods & Facilities

Chair Paolo Mariani · UNIVPM (Ancona, Italy)

14:10-14:40Brian Kloss
NYSBC (New York, USA)

Membrane protein structural genomics at COMPPÅ
past and present

14:40-15:10Alexis Moreno
Calixar (Lyon, France)

Native membrane proteins for drug discovery

15:10-15:40Bernadette Byrne
Imperial College (London, UK)

New approaches to working with membrane proteins

15:40Coffee Break
14:10-14:40Brian Kloss
NYSBC (New York, USA)

Membrane protein structural genomics at COMPPÅ
past and present

14:40-15:10Alexis Moreno
Calixar (Lyon, France)

Native membrane proteins for drug discovery

15:10-15:40Bernadette Byrne
Imperial College (London, UK)

New approaches to working with membrane proteins

15:40Coffee Break

Session 2: Membrane Proteins in Pharmacology and Disease

Chair Alberto Boffi · Sapienza University of Rome

16:10-16:40Antonella De Matteis
Tigem (Naples, Italy)

Membrane remodelling: lessons from coronaviruses

16:40-17:10Cesare Indiveri
Calabria University (Arcavacata di Rende, Italy)

Membrane transporters and novel targets in drug discovery

17:10-17:40Bjoern Windshuegel
IME-Fraunhofer (Hamburg, Germany)

Computational Approaches for Early Stage Drug Discovery

20:00Workshop Dinner
16:10-16:40Antonella De Matteis
Tigem (Naples, Italy)

Membrane remodelling: lessons from coronaviruses

16:40-17:10Cesare Indiveri
Calabria University (Arcavacata di Rende, Italy)

Membrane transporters and novel targets in drug discovery

17:10-17:40Bjoern Windshuegel
IME-Fraunhofer (Hamburg, Germany)

Computational Approaches for Early Stage Drug Discovery

20:00Workshop Dinner

Day 2 – March 4th, 2022
Sapienza University of Rome, Aula degli Organi Collegiali

8:55-9:00OPENING

Francesco Malatesta
Sapienza University of Rome

8:55-9:00OPENING

Francesco Malatesta
Sapienza University of Rome

Session 3: Structural session – The prokaryotic world

Chair Linda C. Montemiglio · CNR – IBPM (Rome, Italy)

9:00-9:30Filippo Mancia
Columbia University (New York, USA)

Structural basis of lipopolysaccharide biosynthesis

9:30-10:00Margarida Archer
ITQB-UNL (Lisbon, Portugal)

The intricate mode of action of arabinofuranosyltransferases in mycobacteria

10:00-10:30Camilo Perez
Biozentrum (Basel, CH).

Mechanism of Cell Wall Transporters Involved in Teichoic Acids Synthesis

10:30Coffee Break
9:00-9:30Filippo Mancia
Columbia University (New York, USA)

Structural basis of lipopolysaccharide biosynthesis

9:30-10:00Margarida Archer
ITQB-UNL (Lisbon, Portugal)

The intricate mode of action of arabinofuranosyltransferases in mycobacteria

10:00-10:30Camilo Perez
Biozentrum (Basel, CH).

Mechanism of Cell Wall Transporters Involved in Teichoic Acids Synthesis

10:30Coffee Break

Session 4: Structural session – The eukaryotic world

Chair Beatrice Vallone · Sapienza University of Rome

11:00-11:30 Francesca Vallese
Columbia University (New York, USA)

Architecture of the human erythrocyte ankyrin-1 complex

11:30-12:00Francesca Magnani
Pavia University (Pavia, Italy)

Structure determination of membrane proteins, from GPCRs to the elusive NADPH oxidases and solute carriers

12:00-12:30Anna Moroni
Milano University (Milan, Italy)

Vidēre est credere: the high resolution structure of the pacemaker channel HCN4

12:30-13:00Discussion & Remarks
11:00-11:30 Francesca Vallese
Columbia University (New York, USA)

Architecture of the human erythrocyte ankyrin-1 complex

11:30-12:00Francesca Magnani
Pavia University (Pavia, Italy)

Structure determination of membrane proteins, from GPCRs to the elusive NADPH oxidases and solute carriers

12:00-12:30Anna Moroni
Milano University (Milan, Italy)

Vidēre est credere: the high resolution structure of the pacemaker channel HCN4

12:30-13:00Discussion & Remarks
 
Maps were disabled by the visitor on this site. Click to open the map in a new window.
Online Attendance Attendance in Person
Watch Day 1 Watch Day 2
Share this entry
  • Share on Facebook
  • Share on Twitter
  • Share on Whatsapp
  • Share on LinkedIn
  • Share by Mail

LATEST NEWS

February 25, 2022

Integrated Structural Biology Approach for Membrane Protein Research
Rome 3rd and 4th March 2022

November 1, 2021

Beatrice Vallone from Sapienza visited Extremochem

July 17, 2020

Prometeus Coordinator, Beatrice Vallone, elected EMBO Member

July 5, 2020

NanoInnovation 2020 postponed! 15-18 September, Rome

June 15, 2020

The Prometeus-Rise Collaboration Unveils the Key that Grants Iron Access to Cells

May 28, 2020

3D structure of anti-tuberculosis target makes cover of Molecular Cell

May 17, 2020

Together we are stronger than Coronavirus

February 14, 2020

Launch of the 2020 edition of the EU Prize for Women Innovators

December 3, 2019

Prometeus was present @ ITQB Nova open day

October 25, 2019

THANK YOU!

July 1, 2019

Mandatory Registration for 10th and 11th October 2019 Conference.

June 29, 2019

Accommodation for 10th and 11th October 2019 Conference

May 14, 2019

10th and 11th October 2019 – Cryo-Electron Microscopy in structural biology. A conference in memory of Emilia Chiancone.

February 20, 2019

Seminar on the structure of the ryanodine receptor by Amédée des Georges from ASRC-CUNY

February 19, 2019

The Prometeus Projects holds its Kick-off Meeting in Rome at Sapienza University.

February 3, 2019

Collegues cheer Gabriele Cerutti the first Prometeus secondee

PROTEIN
and
MEMBRANE
TECHNOLOGY
CONSORTIUM

The Protein and Membrane Technology Consortium (ProMeTeus) promotes the integration of Academia and SME in combining excellent science with entrepreneurial approach and high-throughput methodologies.

This project has received funding from the European Union’s H2020-MSCA-RISE-2018 Research and Innovation program under the Marie Skłodowska-Curie

Grant Agreement No. 823780

© Copyright: PROMETEUS | PRIVACY POLICY | Webdesign FABIO BALDANELLO
Beatrice Vallone from Sapienza visited Extremochem
Scroll to top

This site uses cookies. By continuing to browse the site, you are agreeing to our use of cookies.

OKLearn more

Cookie and Privacy Settings



How we use cookies

We may request cookies to be set on your device. We use cookies to let us know when you visit our websites, how you interact with us, to enrich your user experience, and to customize your relationship with our website.

Click on the different category headings to find out more. You can also change some of your preferences. Note that blocking some types of cookies may impact your experience on our websites and the services we are able to offer.

Essential Website Cookies

These cookies are strictly necessary to provide you with services available through our website and to use some of its features.

Because these cookies are strictly necessary to deliver the website, you cannot refuse them without impacting how our site functions. You can block or delete them by changing your browser settings and force blocking all cookies on this website.

Google Analytics Cookies

These cookies collect information that is used either in aggregate form to help us understand how our website is being used or how effective our marketing campaigns are, or to help us customize our website and application for you in order to enhance your experience.

If you do not want that we track your visist to our site you can disable tracking in your browser here:

Other external services

We also use different external services like Google Webfonts, Google Maps and external Video providers. Since these providers may collect personal data like your IP address we allow you to block them here. Please be aware that this might heavily reduce the functionality and appearance of our site. Changes will take effect once you reload the page.

Google Webfont Settings:

Google Map Settings:

Vimeo and Youtube video embeds:

Privacy Policy

You can read about our cookies and privacy settings in detail on our Privacy Policy Page.

Privacy Policy
Accept settingsHide notification only